Do NAD Supplements Really Work for Anti-Aging? Experts Weigh In

Doctor showing supplement bottle

NAD supplements have become a hot trend, promoted by influencers and podcasters who claim they can reverse aging and boost cognitive function. But do they actually deliver on these promises? While the supplements are gaining popularity, experts caution that there’s no solid scientific proof to back their supposed anti-aging benefits.

Nicotinamide adenine dinucleotide (NAD) is a vital coenzyme found in every cell of the body, playing a key role in energy metabolism. However, levels of this compound naturally decline with age, which is believed to contribute to several age-related health issues, including dementia, diabetes, and cardiovascular disease. Some studies on animals have shown that boosting NAD could improve mitochondrial function, insulin regulation, and cognition. But human studies have not yet shown conclusive results.

Dr. Sarah Espinoza, Director of Translational Geroscience at Cedars-Sinai, explains that while NAD levels decrease with age, short-term use of NAD supplements has not shown significant cognitive improvements in humans. “There are no major adverse effects from taking the supplement for a short period of time,” she told ABC7, noting that it can increase NAD levels in blood cells. However, she stresses that more research is needed before making definitive claims about its anti-aging effects. NAD supplements remain widely available in oral, intravenous, and injectable forms. However, experts argue that there is no evidence suggesting that intravenous or injectable NAD is more effective than the oral version.

As for the price, NAD supplements can range anywhere from $20 to $150 per month, depending on the brand and dosage. While some people swear by their benefits, experts urge caution until more research confirms their effectiveness in slowing down the aging process or enhancing cognitive function.